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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -RAB7 (Ras-related Protein Rab-7a, RAB7A, FLJ20819, PRO2706)

Anti -RAB7 (Ras-related Protein Rab-7a, RAB7A, FLJ20819, PRO2706)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Rab7 is a 207aa transport carrier, belonging to the Rab family of RAS-related GTP-binding proteins with 4 GTP:GDP-binding sites and terminates in sequences such as cys-X-cys, cys-cys or a closely related sequence. Rab7 located in specific intracellular compartments is known to be an important regulator of vesicular transport of proteins from early to late endosomes and lysosome biogenesis. Rab7 accelerates thyroid hormone production controlling aggregation and fusion of late lysosomes. It is ubiquitously expressed in most of the tissues and plays an essential role in maintenance of the perinuclear lysosome compartment.
Catalog #R0008-40B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml
Immunohistochemistry (paraffin): 10ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHeLa cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa90-140 of human Rab7 protein.
SpecificityRecognizes human Rab7. Species Crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesRAB7A, Member RAS Oncogene Family


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