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You are here:Home » Antibodies » Abs to GTPase, Rab, Ras, Rho Proteins » Anti -Rap2B (Member of RAS oncogene family, Ras-related protein Rap-2b precursor)

Anti -Rap2B (Member of RAS oncogene family, Ras-related protein Rap-2b precursor)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Rap2B is a member of the small GTPase superfamily and ras family of proteins. Unlike
normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B
has a threonine residue in that position. This change makes the intrinsic GTPase
activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer
period of time than normal ras proteins. Aggregation of platelets by thrombin results in
the activation of Rap2B in a Ca 2+ and PI3 kinase-dependent manner.
Catalog #R1120-35
ApplicationsSuitable for Western Blot. Other applications not tested.
StorageLyophilized samples are stable for twelve months from date of receipt when stored
at -20°C to -70°C. Upon reconstitution, the antibody can be stored at 2°-8°C for
1 month without detectable loss of activity. Reconstituted antibody can also be
aliquotted and stored frozen at -20°C to -70°C in a manual defrost freezer for
six months without detectable loss of activity. Avoid repeated freeze-thaw cycles.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9H175
HostMouse
SourceHuman
ConcentrationAs reported
Form0.2um sterile-filtered solution in PBS with 5% trehalose.
PurityPurified by Protein G affinity chromatography.
ImmunogenE. coli-derived rhRap2B.
SpecificityThis antibody detects endogenous human Rap2B at 22 kDa using Western blot. The
antibody does not cross-react with recombinant human Rap2A.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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