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Abs to GTPase, Rab, Ras, Rho Proteins
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Anti -Rap2B (Member of RAS oncogene family, Ras-related protein Rap-2b precursor)
Anti -Rap2B (Member of RAS oncogene family, Ras-related protein Rap-2b precursor)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
B |
|
| Rap2B is a member of the small GTPase superfamily and ras family of proteins. Unlike | | | normal ras proteins that have a nontransforming glutamine residue at aa 61, Rap2B | | | has a threonine residue in that position. This change makes the intrinsic GTPase | | | activity for Rap2B lower, thereby allowing it to exist in the activated state for a longer | | | period of time than normal ras proteins. Aggregation of platelets by thrombin results in | | | the activation of Rap2B in a Ca 2+ and PI3 kinase-dependent manner. | | | Catalog # | R1120-35 | | Applications | Suitable for Western Blot. Other applications not tested. | | Storage | Lyophilized samples are stable for twelve months from date of receipt when stored | | at -20°C to -70°C. Upon reconstitution, the antibody can be stored at 2°-8°C for | | 1 month without detectable loss of activity. Reconstituted antibody can also be | | aliquotted and stored frozen at -20°C to -70°C in a manual defrost freezer for | | six months without detectable loss of activity. Avoid repeated freeze-thaw cycles. | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 9H175 | | Host | Mouse | | Source | Human | | Concentration | As reported | | Form | 0.2um sterile-filtered solution in PBS with 5% trehalose. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | E. coli-derived rhRap2B. | | Specificity | This antibody detects endogenous human Rap2B at 22 kDa using Western blot. The | | antibody does not cross-react with recombinant human Rap2A. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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