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R1170-02G Rabbit Anti-Raptor (Regulatory-associated Protein of mTOR, Raptor, P150 Target of Rapamycin (TOR)-scaffold Protein, RPTOR, KIAA1303) (Not for Export EU)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Serum
Applications
WB
Crossreactivity
Hu Mo
Accession #
NP_065812
Shipping Temp
Blue Ice
Storage Temp
-20°C

Regulatory associated protein of mTOR (RAPTOR) is a binding partner of target of rapamycin (TOR). It binds to 4EBP1 and p70alpha. The binding of raptor to mTOR is essential for the mTOR-catalyzed phosphorylation of 4EBP1 in vitro. It enhances the mTOR kinase activity toward p70alpha. It is also an essential scaffold for the mTOR-catalyzed phosphorylation of 4EBP1 and mediates TOR action in vivo.

Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000-1:2000 Optimal dilutions to be determined by the researcher.
Positive Control
Human 293 or mouse NIH 3T3 tumor cell line
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Synthetic peptide corresponding to aa900-950 of human RAPTOR.
Form
Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
Purity
Purified by Rabbit Serum.
Specificity
Recognizes human Raptor. Species Crossreactivity: mouse. Species sequence homology: rat and canine.
References
1. Okazaki N et al, DNA Res. 2003 Aug 31; 10(4):167-80. 2. Hara K et al, Cell. 2002 Jul 26; 110(2):177-89.
USBio References
No references available
Conjugates
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