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S1003-03A Mouse Anti-Serum Amyloid P, Rat (SAP, APCS, PTX2, mature chain 204aa, chromosome 1q21-23)

Specifications
Clone Type
Monoclonal
Host
Mouse
Source
Rat
Swiss Prot
P23680
Isotype
IgG2a
Clone Number
7H67
Grade
Affinity Purified
Applications
E
Crossreactivity
Rt
Shipping Temp
Blue Ice
Storage Temp
-20°C

Pentraxin 2, also known as Serum Amyloid P-Component (SAP), is a hepatocyte-derived glycoprotein that is a nonfibrillar component of amyloid deposits. Pentraxins have a characteristic pentagonal discoid arrangement of five non-covalently bound subunits. Plasma levels of SAP in rat are relatively constant during an acute phase immune response. SAP functions as an opsonin and interacts with Fc-Gamma receptors. The 26 kD, 208 amino acid (aa) mature rat SAP shares 79% and 70% aa identity with mouse and human SAP, respectively.

Applications
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution
ELISA: 0.5-1ug/ml Optimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
NS0-derived recombinant rat Pentraxin 2 (aa21-288) UniProt # P23680
Form
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 1ml sterile PBS.
Purity
Purified by Protein G affinity chromatography.
Specificity
Recognizes rat Pentraxin 2.
Conjugates
Pricing
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