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You are here:Home » Antibodies » Abs to Transcription Factors, STAT » Anti -STAT2 (Signal transducer and activator of transcription 2, ISGF-3, MGC59816, p113, P113, Signal transducer and activator of transcription 2, STAT113)

Anti -STAT2 (Signal transducer and activator of transcription 2, ISGF-3, MGC59816, p113,
P113, Signal transducer and activator of transcription 2, STAT113)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Signal transducer and activator of transcription 2 (STAT2) is a member of the transcription factor
STAT family with an apparent M.W. of 113kD in SDS-PAGE gels. Human STAT2 is 851aa in length and contains one SH2 domain (aa572-667). Splicing variants produce two isoforms for human STAT2. The short isoform has a 32aa substitution and a 199aa deletion corresponding to aa 621-652 and aa653-851 in the long isoform, respectively. Human STAT2 shares 73% and 65% aa sequence identity with rat and mouse STAT2, in that order. STAT2 functions as a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta), and it is also required for myogenic differentiation.
Catalog #S7969-83
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile 40-50% glycerol, PBS.. Aliquot and store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9H181
HostMouse
SourceHuman
Concentration~500ug/ml
FormSupplied as a lyophilized powder in 0.2um sterile-filtered solution in PBS, 5% trehalose. Reconstitute with 40-50% glycerol, PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant human STAT2 aa679-851; P52630 (E. coli).
SpecificityRecognizes human STAT2 at ~115kD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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