Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Toll Like Receptors (TLR) » Anti -TLR2 (Toll Like Receptor 2, CD282, TIL4)

Anti -TLR2 (Toll Like Receptor 2, CD282, TIL4)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified IP IH FC
Toll-like receptor 2 (TLR2) is expressed on smooth muscle, lung, spleen, thymus, brain and adipose tissue and plays a role in pathogen recognition and activation of the innate immune response to pathogens. Specifically it interacts with LY96 to mediate the immune response to bacterial lipoproteins and other microbial cell wall components. It activates NF-kappa-B, via MyD88 and TRAF6, leading to cytokine secretion and the inflammatory response. It may also promote apoptosis in response to lipoproteins. T8050-15F has been reported to inhibit CD282-dependent cell activation in vitro and in vivo.
Catalog #T8050-15F
ApplicationsSuitable for use in Flow Cytometry, Immunohistochemistry (frozen), and Immunoprecipitation. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:5-1:10; 10ul labels 10e6 cells in 100ul.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9i121
HostMouse
SourceMouse
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenRecombinant extracellular domain of mouse CD282.
SpecificityRecognizes mouse CD282, also known as Toll­like receptor 2 (TLR2). Species Crossreactivity: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links