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Anti -Torc1 (Transducer of Regulated CREB Activity 1)
Anti -Torc1 (Transducer of Regulated CREB Activity 1)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E IH |
|
| TORC1, also known as CREB-regulated transcription coactivator 1 (crtc1), is a 67kD member of the TORC family. Mouse TORC1 is 630aa in length. It contains multiple potential sites for phosphorylation and a serine-rich region from aa295-365. Mouse TORC1 is 97% and 90% aa identical to rat and human TORC1, respectively. TORC1 is highly expressed in specific regions of the brain including the cortex, hippocampus, and striatum. It functions as a transcription coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites. | | | Catalog # | T8067-55B | | Applications | Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: 25ug/ml | | Optimal dilutions to be determined by the researcher. | | Hybridoma | Mouse myeloma cells with B cells obtained from a rat immunized with purified, E. coli-derived, recombinant mouse TORC1 (aa384-471). | | Storage and Stability | Lyophilized powder may be stored at -20°C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG2A | | Clone No | 9L860 | | Host | Rat | | Source | Mouse | | Concentration | As reported | | Form | Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | E. coli-derived, recombinant mouse TORC1 (aa384-471; Accession # Q68ED7). | | Specificity | Recognizes mouse TORC1. Species sequence homology: rat (97%), human (90%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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