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You are here:Home » Antibodies » Abs to Transcription Factors » Anti -Torc1 (Transducer of Regulated CREB Activity 1)

Anti -Torc1 (Transducer of Regulated CREB Activity 1)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E IH
TORC1, also known as CREB-regulated transcription coactivator 1 (crtc1), is a 67kD member of the TORC family. Mouse TORC1 is 630aa in length. It contains multiple potential sites for phosphorylation and a serine-rich region from aa295-365. Mouse TORC1 is 97% and 90% aa identical to rat and human TORC1, respectively. TORC1 is highly expressed in specific regions of the brain including the cortex, hippocampus, and striatum. It functions as a transcription coactivator for CREB1, which activates transcription through both consensus and variant cAMP response element (CRE) sites.
Catalog #T8067-55B
ApplicationsSuitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: 25ug/ml
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells obtained from a rat immunized with purified, E. coli-derived, recombinant mouse TORC1 (aa384-471).
Storage and StabilityLyophilized powder may be stored at -20°C for short-term only. Reconstitute with sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2A
Clone No9L860
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with sterile PBS.
PurityPurified by Protein G affinity chromatography.
ImmunogenE. coli-derived, recombinant mouse TORC1 (aa384-471; Accession # Q68ED7).
SpecificityRecognizes mouse TORC1. Species sequence homology: rat (97%), human (90%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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