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Abs to Transcription Factors, TRIM (Tripartite Motif)
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Anti -TRIM (T Cell Receptor-Interacting Molecule)
Anti -TRIM (T Cell Receptor-Interacting Molecule)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B FC |
|
| Human TRIM (T cell receptor–interacting molecule) (also trat1; T cell receptor-associated transmembrane adaptor 1, and pp29/30) is a 27-30kD, type III transmembrane protein, that is a member of the transmembrane adaptor protein (TRAP) family. It contains a short, 8 amino acid (aa) extracellular region, a 19 aa transmembrane region, and a 159 aa cytosolic tail. Its cytoplasmic tail contains several tyrosine motifs with the potential to bind to Src-homology 2 (SH2) domains of signaling proteins. TRIM is present in T cells and NK cells. Human TRIM shares 66% aa sequence identity with mouse TRIM. | | | Catalog # | T8464-35B | | Applications | Suitable for use in Flow Cytometry, Direct ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | Flow Cytometry: 25ug/ml use 10ul to label 10e6 cells. | | Direct ELISA: 0.5-1.0ug/ml detection limit for rhTRIM is ~ 0.3ng/well. | | Western Blot: 1.0ug/ml. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Reconstitute to nominal volume by adding sterile 40-50% glycerol, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | As reported | | Form | Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitute with 500ul sterile 40-50% glycerol, PBS. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | E. coli-derived rhTRIM. (aa 49 - 186) | | Specificity | Recognizes human TRIM. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Trat1, T cell Receptor-associated Transmembrane Adaptor 1, pp29/30 |
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