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Anti -Vascular Endothelial Statin (VE-Statin, EGF-Like Domain-containing Protein 7, EGFL7)
Anti -Vascular Endothelial Statin (VE-Statin, EGF-Like Domain-containing Protein 7, EGFL7)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Rat |
Affinity Purified |
E B |
|
| Mouse VE-Statin (vascular endothelial cell statin; also EGFL7) is a 41 kD, secreted glycoprotein that belongs to an expanding family of EGF-like domain-containing proteins. It is an early marker of embryonic endothelial cells, and occurs in adult endothelium. Its secretion blocks smooth muscle migration. The mature molecule is 254 amino acids (aa) in length, and contains one N-terminal EMI domain (aa 28-105), two EGF-like domains (aa 106-178), and a coiled-coil region (aa 196-220). There is at least one isoform that shows a 13 aa deletion between aa 236-248. Mature mouse VE-statin is 76% and 80% identical to dog and human VE-statin, respectively. | | | Catalog # | V2111-05 | | Applications | Suitable for use in Western Blot and ELISA. Other applications not tested. | | Recommended Dilution | Western Blot: 1-2ug/ml | | ELISA: 0.5-1ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2b | | Clone No | 7H138 | | Host | Rat | | Source | Mouse | | Concentration | As reported | | Form | Supplied as a lyophilized powder from a 0.2um filtered solution in PBS, 5% trehalose. Reconstitute with 1ml sterile, ddH2O or sterile 40-50% glycerol. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | E. coli-derived recombinant mouse VE-statin (aa21-275) Accession #Q9QXT5 | | Specificity | Recognizes mouse VE-Statin. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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