Binds to 5S ribosomal RNA By similarity. Required for rRNA maturation and formation of the 60S ribosomal subunits. Promotes nucleolar location of PML By similarity.
Suitable for use in FLISA and Western Blot. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. FITC conjugates are sensitive to light.
| As reported|
|Recombinant corresponding to human 60S ribosomal. L11.|
|Purified by ammonium sulfate precipitation.|
|Supplied as a liquid in 0.01M PBS, PH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with fluorescein isothiocyanate (FITC).|
|Recognizes human RPL11.|
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
1. "Cloning and determination of the primary structure of DNA complementary to the mRNA of human ribosomal protein L11." Mishin V.P., Filipenko M.L., Muravlev A.I., Karpova G.G., Mertvetsov N.P. Bioorg. Khim. 21:158-160(1995). 2. "Structural and functional analysis of the human ribosomal protein L11 gene." Voronina E.N., Kolokol'tsova T.D., Nechaeva E.A., Filipenko M.L. Mol. Biol. (Mosk.) 37:425-435(2003). 3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004).|