Technical Data
029454
DNP (Dinitrophenol)
Description:
Dinitrophenol is a small water-soluble, hydrophobic ligand that binds to transthyretin at acidic pH and also reduces the formation of amyloid fibril. DNP levels of 100mg/ml or more is greatly toxic to acclimated bacteria. DNP has been associated with possible therapies for neurodegenerative and neurological disorders.

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilutions:
Western Blot: 0.5ug/ml detected DNP on 10ug of Oxyblot protein standards
Optimal dilutions to be determined by the researcher.

Positive Control:
Oxyblot protein standards

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG1,k13A173Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
DNP, conjugated to KLH
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in 0.1M Tris-glycine, pH 7.4, 150mM sodium chloride, 0.05% sodium azide.
Specificity:
Recognizes DNP. Species Crossreactivity: all species
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. DeFelice, F.G. and Ferreira, S.T. (2006). IUBMB Life. 58(4):185-191. 2. Jo, K.H. Silverstein, J. (2004). Water Sci Technol. 50(5):45-50. 3. Raghu, P., et al. (2002). Arch Biochem Biophys. 400(1):43-47.