Technical Data
ACVR1B (ACVRLK4, ALK4, Activin receptor type-1B, Activin receptor type IB, Activin receptor-like kinase 4, Serine/threonine-protein kinase receptor R2)
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Suitable for use in Western Blot, ELISA.

Recommended Dilution:
ELISA: 1:1000
Western Blot: 1?500~4000

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage, store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
100ul-20CBlue IceHumanMouse
As reported
ACVR1B Mab was raised using purified His-tagged recombinant human ACVR1B.
Supplied as a liquid, crude ascites with 0.09% sodium azide.
Human, mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010)
Suzuki, K., et al. Biochem. Biophys. Res. Commun. 394(3):639-645(2010)
Calvanese, L., et al. J. Pept. Sci. 15(3):175-183(2009)
Esguerra, C.V., et al. Development 134(24):4381-4393(2007)
Maguire, P.B., et al. Proteomics 2(6):642-648(2002)