Technical Data
031528
ACCN2, CT (ASIC1, ACCN2, BNAC2, Acid-sensing ion channel 1, Amiloride-sensitive cation channel 2, neuronal, Brain sodium channel 2)
Description:
ACCN2 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Flow Cytometry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
ACCN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 499~528 amino acids from the C-terminal region of human ACCN2.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Sherwood,T., et.al., J. Biol. Chem. 284 (41), 27899-27907 (2009)
Kapoor,N., et.al., J. Biol. Chem. 284 (36), 24526-24541 (2009)
Samways,D.S., et.al., Cell Calcium 45 (4), 319-325 (2009)