Technical Data
AGER, NT (AGER, RAGE, Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products)
AGER encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6.

Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As Reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 24-52 in the N-terminal region of human AGER, UniProt Accession #Q15109 Cellular Localization: Cell membrane; Single-pass type I membrane protein.
Purified by Protein A affinity chromatography
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human AGER. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Rojas, A., et al. Carcinogenesis 31(3):334-341(2010). 2. Engelen, L., et al. J. Hypertens. 28(2):285-293(2010). 3. Poon, P.Y., et al. Clin. Nephrol. 73(1):44-50(2010). 4. Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)