Technical Data
031693
AGER, NT (AGER, RAGE, Advanced glycosylation end product-specific receptor, Receptor for advanced glycosylation end products)
Description:
AGER encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications not tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As Reported
Immunogen:
KLH-conjugated synthetic peptide derived from within amino acids 24-52 in the N-terminal region of human AGER, UniProt Accession #Q15109. Cellular Localization: Cell membrane; Single-pass type I membrane protein
Purity:
Purified by Protein A affinity chromatography
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human AGER. Species Crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Rojas, A., et al. Carcinogenesis 31(3):334-341(2010). 2. Engelen, L., et al. J. Hypertens. 28(2):285-293(2010). 3. Poon, P.Y., et al. Clin. Nephrol. 73(1):44-50(2010). 4. Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)