Technical Data
031714
AHR, ID (AHR, BHLHE76, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76)
Description:
AHR is a ligand-activated transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Its ligands included a variety of aromatic hydrocarbons. [provided by RefSeq].

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and Flow Cytometry. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Immunofluorescence: 1:10-1:50
Flow Cytometry: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As Reported
Immunogen:
Synthetic peptide corresponding to aa555-582 from the Central region of human AHR (NP_001612), conjugated to KLH.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human AHR. Species crossreactivity: mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Davila, S., et al. Genes Immun. (2010) In press : Kalthoff, S., et al. J. Biol. Chem. 285(9):5993-6002(2010) Hall, J.M., et al. Mol. Endocrinol. 24(2):359-369(2010) Schroeder, J.C., et al. Biochemistry 49(2):393-400(2010)