Technical Data
031779
ALDH6A1, NT (ALDH6A1, MMSDH, Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial, Aldehyde dehydrogenase family 6 member A1)
Description:
ALDH6A1 belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. This protein is a mitochondrial methylmalonate semialdehyde dehydrogenase, and catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-100
Immunohistochemistry: 1:10-50
Flow Cytometry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
ALDH6A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37~67 amino acids from the N-terminal region of human ALDH6A1.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Kuiper,H., Cytogenet. Genome Res. 109 (4), 533 (2005)
Anderson,N.L., Mol. Cell Proteomics 3 (4), 311-326 (2004)
Chambliss,K.L., J. Inherit. Metab. Dis. 23 (5), 497-504 (2000)
Kedishvili,N.Y., J. Biol. Chem. 267 (27), 19724-19729 (1992)