Technical Data
032523
BIRC2, ID (BIRC2, API1, IAP2, MIHB, RNF48, Baculoviral IAP repeat-containing protein 2, C-IAP1, IAP homolog B, Inhibitor of apoptosis protein 2, RING finger protein 48, TNFR2-TRAF-signaling complex protein 2)
Description:
The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals.

Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
BIRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the Central region of human BIRC2.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Hinz, M., et al. Mol. Cell 40(1):63-74(2010)
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Meng, N., et al. J. Cell. Physiol. 225(1):174-179(2010)
Burke, S.P., et al. J. Biol. Chem. 285(39):30061-30068(2010)
Mace, P.D., et al. J. Mol. Biol. 400(1):8-15(2010)