Technical Data
033144
CALCA, ID (CALCA, CALC1, Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I)
Description:
This gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. Calcitonin is involved in calcium regulation and acts to regulate phosphorus metabolism. Calcitonin gene-related peptide functions as a vasodilator while katacalcin is a calcium-lowering peptide. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As Reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 56-83 in the central region of human CALCA, UniProt Accession #P06881.
Purity:
Purified by Protein A affinity chromatography
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide
Specificity:
Recognizes human CALCA.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Giroux, S., et al. Bone 47(5):975-981(2010). 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). 3. Lee, J.Y., et al. Korean J Lab Med 30(4):406-413(2010). 4. Giovanella, L., et al. Clin. Chem. Lab. Med. 48(8):1163-1165(2010). 5. Hatzistilianou, M. ScientificWorldJournal 10, 1941-1946 (2010)