Technical Data
033765
CENPE, CT (CENPE, Centromere-associated protein E, Centromere protein E, Kinesin-related protein CENPE)
Description:
Centrosome-associated protein E is a kinesin-like motor protein that accumulates in the G2 phase of the cell cycle. Unlike other centrosome-associated proteins, it is not present during interphase and first appears at the centromere region of chromosomes during prometaphase. CENPE is proposed to be one of the motors responsible for mammalian chromosome movement and/or spindle elongation.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
CENPE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2572-2602 amino acids from the C-terminal region of human CENPE.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Kim, Y., et al. Cell 142(3):444-455(2010)
Maia, A.F., et al. Chromosoma 119(4):405-413(2010)
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)
Maffini, S., et al. Curr. Biol. 19(18):1566-1572(2009)
Liu, Z., et al. J. Exp. Clin. Cancer Res. 28, 156 (2009) :