Technical Data
035103-PE
EPAS1, NT (EPAS1, BHLHE73, HIF2A, MOP2, PASD2, Endothelial PAS domain-containing protein 1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73, HIF-1-alpha-like factor, Hypoxia-inducible factor 2-alpha, Member of PAS protei
Description:
This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

Applications:
Suitable for use in Western Blot, Flow Cytometry, FLISA

Recommended Dilution:
FLISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50

Storage and Stability:
Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul4C Do Not FreezeBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
EPAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-154 amino acids from the N-terminal region of human EPAS1.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (R-PE).
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Yi, X., et al. Science 329(5987):75-78(2010)
Bougatef, F., et al. PLoS ONE 5 (8), E12265 (2010) :
Hossein Ghaderian, S.M., et al. Pathology 42(5):446-453(2010)
Mowat, F.M., et al. PLoS ONE 5 (6), E11103 (2010) :