Technical Data
MUC20, NT (MUC20, KIAA1359, Mucin-20)
This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The shorter isoform expressed by this gene is localized to the plasma membrane, whereas the longer isoform might be secreted. The C terminus of this protein associates with the multifunctional docking site of the met proto-oncogene and suppresses activation of some downstream met signaling cascades. The protein features a tandem repeat domain that varies between 2 and 6 copies in different individuals. Multiple transcript variants encoding different isoforms have been found for this gene.

Suitable for use in ELISA, Western Blot and Immunofluorescence. Other applications have not been tested.

Recommended Dilution:
Western Blot: 1:1000
Immunofluorescence: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
200ul-20CBlue IceHumanRabbit
As reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 61-90 in the N-terminal region of human MUC20, UniProt Accession #Q8N307.
Purified by ammonium sulfate precipitation.
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Recognizes human MUC20.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Li,G., Am. J. Nephrol. 26 (1), 43-49 (2006) Suzuki,Y., Genome Res. 14 (9), 1711-1718 (2004) Higuchi,T., Mol. Cell. Biol. 24 (17), 7456-7468 (2004) Higuchi,T., J. Biol. Chem. 279 (3), 1968-1979 (2004)