Technical Data
041159
RNT2, NT (RNASET2, RNASE6PL, Ribonuclease T2, Ribonuclease 6)
Description:
This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement.

Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested.

Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:50-1:100
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As Reported
Immunogen:
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 10-36 in the N-terminal region of human RNT2, UniProt Accession #O00584.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Recognizes human RNT2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Fransen, K., et al. Hum. Mol. Genet. 19(17):3482-3488(2010). 2. Quan, C., et al. Nat. Genet. 42(7):614-618(2010). 3. Liu, J., et al. J. Cell. Mol. Med. 14(5):1146-1155(2010). 4. Henneke, M., et al. Nat. Genet. 41(7):773-775(2009). 5. Monti, L., et al. Oncol. Res. 17(2):69-74(2008)