Technical Data
042650
TBCE, ID (TBCE, Tubulin-specific chaperone E, Tubulin-folding cofactor E)
Description:
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

Applications:
Suitable for use in Western Blot, ELISA

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
TBCE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371~400 amino acids from the Central region of human TBCE.
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Specificity:
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Biernacki, M.A., et al. Cancer Res. 70(3):906-915(2010)
Padidela, R., et al. J. Clin. Endocrinol. Metab. 94(8):2686-2691(2009)
Lindgren, C.M., et al. PLoS Genet. 5 (6), E1000508 (2009)
Jin, S., et al. Development 136(9):1571-1581(2009)
Diaz, G.A., et al. Genomics 54(1):13-18(1998)
Parvari, R., et al. Am. J. Hum. Genet. 63(1):163-169(1998)