Technical Data
DR6, Recombinant, Mouse:Fc (Death Receptor 6, Tumor Necrosis Factor Receptor Superfamily Member 21, TNFRSF21)
Molecular Biology Storage: 4C/-20CShipping: Blue Ice
DR6 is an orphan TNF receptor superfamily member belonging to a subgroup of receptors called death receptors. Expressed ubiquitously with high expression in lymphoid organs, heart, brain, and pancreas. Broadly expressed by developing neurons where it functions as pro-apoptotic factor. Recently, it has been reported that interaction with the beta-amyloid precursor protein (APP) activates a widespread caspase-dependent self-destruction program dependent on caspase-6.

Mouse DR6 (aa 42-348) is fused at the C-terminus to the Fc portion of human IgG1.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 6 months after receipt when stored at -20C.

Molecular Weight:
~80kD (SDS-PAGE)
Source: Human, Mouse, HEK 293 cells
Purity: >95% (SDS-PAGE)
Concentration: 1mg/ml
Form: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.