Technical Data
044790
Ferulenol (2-Hydroxy-3-chromen-4-one)
1mg
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Prenylated 4-hydroxycoumarin. Anti-tumor compound. Cytotoxic. Stimulator of tubulin polymerisation in vitro. Inhibitor of colchicine binding to tubulin. Antitubercular antibiotic with potent antibacterial activity. Anti-coagulant, pro-haemorrhagic compound with higher activity than warfarin. Shows hepatocyte toxicity. Disrupts mitochondrial membrane potential.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 2 years after receipt when stored at -20C.

CAS Number:
6805-34-1

Molecular Formula:
C24H30O3

Molecular Weight:
366.5
Purity: >98% (HPLC)

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Product Reference:
Acute toxicity of ferulenol, a 4-hydroxycoumarin isolated from Ferula communis L: O. Fraigui, et al.; Vet. Hum. Toxicol. 44, 5 (2002)
Microtubule-interacting activity and cytotoxicity of the prenylated coumarin ferulenol: C. Bocca, et al.; Planta Med. 68, 1135 (2002)
Antimycobacterial coumarins from the sardinian giant fennel (Ferula communis): G. Appendino, et al.; J. Nat. Prod. 67, 210 (2004)
Characterization of anti-coagulant properties of prenylated coumarin ferulenol: M. Monti, et al.; Biochim. Biophys. Acta 1770, 1437 (2007)
Ferulenol specifically inhibits succinate ubiquinone reductase at the level of the ubiquinone cycle: M. Lahouel, et al.; BBRC 355, 252 (2007)
Disruption of mitochondrial membrane potential by ferulenol and restoration by propolis extract: antiapoptotic role of propolis: B.H. Nadia, et al.; Acta Biol. Hung. 60, 385 (2009)


Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.