Technical Data
IBMX (3-Isobutyl 1-methylxanthine, NSC 165960, SC2964, EINECS 249-259-3)
Biochemicals Storage: -20CShipping: Blue Ice
Cell permeable, competitive, non-specific cAMP and cGMP phosphodiesterase inhibitor. Increases cAMP levels that activate PKA, leading to decreased proliferation, increased differentiation and induction of apoptosis. Enhances differentiation of 3T3-L1 cells. Non-selective adenosine receptor antagonist. Inhibits Ca2+ ion channels. Activates TNF-alpha. Adipogenic. Activates leukotriene synthesis. Reduces inflammation and innate immunity.

IC50 values are 13, 18, 19, 32 and 50uM for PDE4, PDE3, PDE1, PDE5 and PDE2 respectively

DMSO, Dichloromethane, Ether, Ethyl acetate, Methanol and ethanol. Insoluble in water.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 2 years after receipt when stored at -20C.

CAS Number:

Molecular Formula:

Molecular Weight:
Purity: 99% (HPLC)
Form: Supplied as a white solid.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
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Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.