Technical Data
044997
Latrunculin A (LAT-A, NSC 613011)
100ug
Biochemicals Storage: -20CShipping: Blue Ice
A cell-permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Depolymerizes actin filaments (F-actin) and acts as a phagocytosis inhibitor. Anticancer compound. Suppresses hypoxia-induced HIF-1 activation in tumor cells. Inhibits tumor cell invasion.

Solubility:
DMSO, Ethanol

Molecular Weight:
~421.55

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months after receipt at -20C. Reconstitute with sterile buffer. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
76343-93-6

Molecular Formula:
C22H31NO5S

Molecular Weight:
421.6
Source: Latrunculia magnifica
Purity: >96 (HPLC)
Form: Supplied as a white solid

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.