Technical Data
045074
Necrostatin-5 (Nec-5, 3-p-Methoxyphenyl-5,6-tetramethylenothienopyrimidin-4-one-2-mercaptoethylcyanide)
5mg
Biochemicals Storage: +4C/+4CShipping: Blue Ice
Necroptosis inhibitor. Indirect RIP1 kinase inhibitor.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: +4C
Stable for at least 2 years after receipt when stored at +4C.

CAS Number:
337349-54-9

Molecular Formula:
C19H17N3O2S2

Molecular Weight:
383.5
Purity: >98% (NMR)

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Product Reference:
Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5: K. Wang, et al.; Bioorg. Med. Chem. Lett. 17, 1455 (2007)
Idenfication of RIP1 kinase as a specific cellular target of necrostatins: A. Degterev, et al.; Nat. Chem. Biol. 4, 313 (2008)


Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.