Technical Data
045127
Paprotrain ((Z)-alpha-(3-Pyridinylmethylene)-1H-indole-3-acetonitrile)
1mg
Biochemicals Storage: 4C/-20CShipping: Blue Ice
Cell permeable kinesin-specific MKLP-2 (mitotic kinesin-like protein 2) inhibitor. Inhibits the recruitment of the chromosome passenger proteins survivin and aurora B to the central spindle during anaphase chromosome segregation.

Storage and Stability:
Short-term Storage: +4C
Long-term Storage: -20C
Stable for at least 2 years after receipt when stored at -20C.

CAS Number:
57046-73-8

Molecular Formula:
C16H11N3

Molecular Weight:
245.3
Purity: >98% (NMR)

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Product Reference:
Relocation of Aurora B and Survivin from Centromeres to the Central Spindle Impaired by a Kinesin-Specific MKLP-2 Inhibitor: S. Tcherniuk, et al.; Angew. Chem. (Int'l Ed.) 49, 8228 (2010)


Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.