Technical Data
136827
NAD Biosynth Inhibitor (SIR Down Regulator)
5mg
25mg
Biochemicals Storage: -20CShipping: Blue Ice
Nicotinamide phosphoribosyltransferase inhibitor (Ki=0.4 nM). Induces tumor cell apoptosis.
Extends lifespan of human cells. Cell permeable.

Solubility:
H2O (~40mg/ml)

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
658084-64-1

Molecular Formula:
C24H29N3O2 HCl

Molecular Weight:
428
Source: Synthetic
Purity: ~98% (TLC)
Concentration: Not determined
Form: Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH20.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Hasmann M., et al. (2003) Cancer Res. 63: 7436. 2. van der Veer E., et al. (2007) J. Biol. Chem. 282:10841.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.