Technical Data
A0007-34
ABI1 (ABI1, ABI-1, ABL-interactor 1, E3BP1, EPS8 binding protein, NAP1BP, Nap1 binding protein, SSH3BP, SSH3BP1, Spectrin SH3 domain binding protein 1)
Description:
The protein encoded by this gene has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling. Several transcript variants encoding multiple isoforms have been found for this gene.

Applications:
Suitable for use in Immunoprecipitation. Not suitable for Western Blot. Other applications have not been tested.

Recommended Dilution:
Immunoprecipitation: 2-5ug/mg lysate
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol and aliquot. Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide corresponding to a region between aa150 and 200 of human abl-interactor 1 using the numbering given in entry NP_005461.2 (GeneID 10006).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in tris-citrate/phosphate buffer, pH 7 to 8, 0.09% sodium azide.
Specificity:
Recognizes human ABI1. Epitope maps to a region between aa150 and 200 of human abl-interactor 1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.