Technical Data
ABI1 (ABI1, ABI-1, ABL-interactor 1, E3BP1, EPS8 binding protein, NAP1BP, Nap1 binding protein, SSH3BP, SSH3BP1, Spectrin SH3 domain binding protein 1)
The protein encoded by this gene has been found to form a complex with EPS8 and SOS1, and is thought to be involved in the transduction of signals from Ras to Rac. In addition, the encoded protein may play a role in the regulation of EGF-induced Erk pathway activation as well as cytoskeletal reorganization and EGFR signaling. Several transcript variants encoding multiple isoforms have been found for this gene.

Suitable for use in Immunoprecipitation. Not suitable for Western Blot. Other applications have not been tested.

Recommended Dilution:
Immunoprecipitation: 2-5ug/mg lysate
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add 40-50% glycerol and aliquot. Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
100ug-20CBlue IceHumanRabbit
As reported
Synthetic peptide corresponding to a region between aa150 and 200 of human abl-interactor 1 using the numbering given in entry NP_005461.2 (GeneID 10006).
Purified by immunoaffinity chromatography.
Supplied as a liquid in tris-citrate/phosphate buffer, pH 7 to 8, 0.09% sodium azide.
Recognizes human ABI1. Epitope maps to a region between aa150 and 200 of human abl-interactor 1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.