Technical Data
A0667-19
ACOX1, NT (Peroxisomal Acyl-coenzyme A Oxidase 1, Acyl-coenzyme A Oxidase 1, Peroxisomal, Palmitoyl-CoA Oxidase, AOX, Straight-chain Acyl-CoA Oxidase, SCOX, ACOX)
Description:
ACOX1 is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids.

Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:1,000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
200ul-20CBlue IceHumanRabbit
Concentration:
As reported
Immunogen:
Synthetic peptide selected from the N-terminal region of human ACOX1 (KLH).
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:
Recognizes human ACOX1. Species Crossreactivity: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Strausberg, R.L., et al., Proc. Natl. Acad. Sci. USA 99(26):16899-16903 (2002). 2. Chu, R., et al., J. Biol. Chem. 270(9):4908-4915 (1995). 3. Aoyama, T., et al., Biochem. Biophys. Res. Commun. 198(3):1113-1118 (1994). 4. Fournier, B., et al., J. Clin. Invest. 94(2):526-531 (1994). 5. Varanasi, U., et al., Proc. Natl. Acad. Sci. USA 91(8):3107-3111 (1994).