Technical Data
-Amyloid, 42-1
Molecular Biology Storage: -20°CShipping: Blue Ice
Inactive control against b-Amyloid 1-42, which is a major constituent of plaques and tangles that occur in Alzheimer’s disease (AD) patients.

See A2275-74F for antisense, active peptide.

Sequence (linear): H2N-Ala-Ile-Val-Val-Gly-Gly-Val-Met-Leu-Gly-Ile-Ile-Ala-Gly-Lys-

Storage and Stability:
Lyophilized powder may be stored at 4°C for short-term only. Stable for 6 months at -20°C. Reconstitute (see reconstitution instructions for peptides) and store at -20°C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
Source: Human
Purity: ~70% by HPLC analysis
Concentration: As reported
Form: Supplied as a lyophilized powder (Trifluoroacetate salt)

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Borchelt, D.R. et. al. (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19: 939-945. 2. Arendash, G.W. et al. (1999) Intravascular b-amyloid infusion increases blood pressure: implications for a vasoactive role of b-amyloid in the pathogenesis of Alzheimer’s disease. Neuroscience Letters 268:17-20. 3. Yan, S.D. et al. (1999) Role of ERAB/L-3-hydroxyacyl-coenzyme A dehydrogenase type II activity in Ab-induced cytotoxicity. J. Biol. Chem. 274:2145-2156. 4. Bradt, B.M. et al. (1999) Complement-dependent proinflammatory properties of the Alzheimer’s disease b-peptide. J. Exp. Med. 188:431-438. 5. Eisenhauer, P.B. et al. (2000) Toxicity of various amyloid beta peptide species in cultured human blood-brain barrier endothelial cells: increased toxicity of dutch-type mutant. J. Neurosci. Res. 60(6):804-810.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.