Technical Data
A2295-06
Angiotensin II (Hypertensin II, Ang II)
5mg
25mg
Molecular Biology Storage: -20CShipping: RT
Ang II plays an important role in regulating natriuretic peptide gene expression during cardiac overload. ANP and BNP gene expression in the rat heart is modulated by the adrenal factors during Ang II-stimulated hemodynamic stress and the AT1 receptor antagonism in NO-deficient hypertension. Moreover, ventricular BNP gene expression in Ang II-induced hypertension in vivo is controlled by posttranscriptional mechanisms and GATA elements.

SAA equence: H-Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-OH acetate salt

The sequence given for angiotensin II corresponds to the sequences of human, horse, sheep, pig and rat angiotensins.

Identification:
m=1046.3u (average mass)

Water (KF):
3.0%

Storage and Stability:
Lyophilized powder may be stored at 4C for short-term only. Reconstitute with sterile distilled water and store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

CAS Number:
4474-91-3

Molecular Formula:
C50H71N13O12

Molecular Weight:
1046.19D
Purity: 98% (TEAP; HPLC)
Concentration: ~10mg/ml
Form: Supplied as a lyophilized powder. Reconstitute to 10mg/ml with sterile ddH2O.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. Hahn, A.W.A., et al., J. Cardiovasc. Pharmacol. 22(5): S37 (1993). 2. Takei, Y., et al., Gen. Comp. Endocrinol. 90: 214 (1993). 3. Ardaillou, R. and D. Chansel, Kidney International 52: 1,458 (1998).

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.