Technical Data
Antibiotic TPU-0037-A (30-Demethyl-lydicamycin)
Biochemicals Storage: -20CShipping: Blue Ice
TPU-0037A, a close structural analogue of lydicamycin, has been shown to be highly active against MRSA. TPU-0037A is also closely related to Antibiotic BN 4515N isolated from a strain of Microtetraspora as a neuritogenic agent.

Soluble in ethanol, methanol, DMF or DMSO.

Storage and Stability:
May be stored at -20C. Reconstitute to nominal volume. Aliquot and store at -20C. Reconstituted product is stable for 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer

CAS Number:

Molecular Formula:

Molecular Weight:
Source: Streptomyces sp.
Purity: ~95% by HPLC.
Form: Supplied as a colorless film.
Specificity: Shown to be highly reactive against MRSA

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
1. TPU-0037-A, B, C and D, novel lydicamycin congeners with anti-MRSA activity from Streptomyces platensis TP-A0598. Furumai T. et al. J. Antibiot. 2002, 55, 873. 2. A new neuritogenetic compound BU-4514N produced by Microtetraspora sp.. Toda S. et al. J. Antibiot. 1993, 46, 875. 3. Lydicamycin, a new antibiotic of a novel skeletal type. II. Physico-chemical properties and structure elucidation. Hayakawa Y. et al. J. Antibiot. 1991, 44, 288. 4. Lydicamycin, a new antibiotic of a novel skeletal type. I. Taxonomy, fermentation, isolation and biological activity. Hayakawa Y. et al. J. Antibiot. 1991, 44, 282.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.