Technical Data
B0085-04A
BRCAA1 (AT Rich Interactive Domain 4B (RBP1-like) isoform 1, RBP1-like Protein, Breast Carcinoma-associated Antigen BCAA, Breast Cancer-associated Antigen BRCAA1, Retinoblastoma-binding Protein 1-like 1, SIN3A-associated Protein 180)
Description:
The novel BRCAA1 protein's epitope, SSKKQKRSHK, was mapped to the cytoplasm of MCF-7 cells. Analysis has shown that the antigen epitope exhibited positive expression in 65% of breast cancer specimens. Its expression is associated with characteristics that are associated with prognosis of breast cancer, and its sera antibody level may be helpful for breast cancer diagnosis.

Positive Control: MCF-7 cell lysate

Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabPurified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanRabbit
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide surrounding residues 1046-1055 of BRCAA1 protein
Purity:
Purified
Form
As reported
Specificity:
Reacts with residues 1046-1055 [SSKKQKRSHK] of the 136kD human, mouse and rat BRCAA1 protein. Not tested in any other species.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Beardsley, D.I., et al. Exp. Cell Res. 290(2):402-413, 2003.
2. Cui, D., et al. Cancer Epidemiol. Biomarkers Prev. 13(7):1136-1145, 2004.