Technical Data
B2570-24C
Borrelia burgdorferi (Lyme Disease)
Description:
Borrelia burgdorferi is a spirochete and the cause of Lyme disease, a tick transmitted illness of humans and animals. B. burgdorferi may persist in humans and animals for months or years following initial infection, despite a robust humoral immune response. B. burgdorferi resembles other spirochetes in that it is a highly specialized, motile, two-membrane, spiral shaped bacteria which lives primarily as an extracellular pathogen. B. burgdorferi has an unusual genome compared with other eubacteria which includes a linear chromosome approximately one megabase in size and numerous linear and circular plasmids.

Applications:
Suitable for use in Immunofluorescence, Immunohistochemistry and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry: Frozen and paraffin sections
Western Blot: Bands at ~83kD, ~41kD, ~34kD and ~31kD. Additional lower MW bands may also be observed
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGPurified
SizeStorageShippingSourceHost
1ml-20CBlue IceRabbit
Concentration:
~1mg/ml
Immunogen:
Whole cell preparation from B. burgdorferi.
Purity:
Purified
Form
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Specificity:
Recognizes B. burgdorferi. Species Crossreactivity: Treponema pallidum, B. hermsi and B. parkerii.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. De Socio, G.V. et al. (2011) Malignant syphilis with ocular involvement in an HIV-infected patient. Int J STD AIDS. 22: 298-300. 2. Drago, F. et al. (2014) Primary syphilis of the oropharynx: unusual location of a chancre Int J STD AIDS. Sep 4. 3. Drago, F. et al. (2012) Luetic lymphadenopathy despite negative serology Int J STD AIDS. 23: 601-2. 4. Acta Derm Venereol. 80: 235-6. (2000) Syphilitic chancre despite use of condoms: "condom chancre". Haedersdal, M. and Weismann, K.