Technical Data
C1385-06A
Cardiotrophin 1, Recombinant, Human (CT1)
10ug
Molecular Biology Storage: -20CShipping: Blue Ice
Source:
Recombinant corresponding to 201aa from human Cardiotrophin 1 expressed in E. coli.

Molecular Weight:
~21.5kD

Activity:
ED50 <1.0 ng/ml (>1 x 106units/mg). The biological activity was determined by measuring the dose-dependent proliferation of TF-1 cells. Cardiotrophin-1 is a member of the IL-6 family of cytokines which includes IL-6, Leukemia Inhibitory Factor, Ciliary Neurotrophic Factor, Oncostatin M and Interleukin 11. The receptor for Cardiotrophin-1 is gp130 (CD130). Cardiotrophin-1 was originally identified by its ability to stimulate cardiac hypertrophy. As with all members of the IL-6 family of cytokines, Cardiotrophin-1 induces hepatic expression of acute phase proteins.

Endotoxin: <0.1 ng/ug

Storage and Stability:
Lyophilized powder may be stored at -20C. Stable for 12 months at -20C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
~21.5kD
Source: E. coli
Purity: ~98% (SDS PAGE, HPLC)
Concentration: Not determined
Form: Supplied as a lyophilized powder in PBS. Reconstitute with sterile dH2O PBS to 0.1-1mg/ml.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.