Description:
Cellular Localization: Cell Membrane
Positive Control: Immunocytochemistry on human peripheral blood leukocytes.
Applications:
Suitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
|
| Type | Isotype | Clone | Grade |
|---|
| Pab | IgG | | Affinity Purified |
|
| Size | | Storage | Shipping | Source | Host |
|---|
| 50ug | | -20°C | Blue Ice | Human | Goat |
|
| Concentration: |
| ~1mg/ml |
| Immunogen: |
| Synthetic peptide: TEDYDTTTEFDYGDATPC, corresponding to amino acids 7 - 24 of Human CCR1. Epitope: N-terminal extracellular domain of human CCR1. |
| Purity: |
| Purified by immunoaffinity chromatography. |
| Form |
| 0.1% Sodium Azide PBS, 1mg/ml BSA. pH 7.2 |
| Specificity: |
| Peptide sequence is < 50% identical to other chemokine receptors in this region. Species Crossreactivity: Crossreacts with Human. Does not crossreact with Mouse. Expected to crossreact with Macaque Monkey (88% identity with immunogen) due to sequence homology. |
|
| Intended for research use only. Not for use in human, therapeutic, or diagnostic applications. |
Neote K et al. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 72:415-25 (1993).
2. Su, S.B., et al. Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression of various types of leukocytes. J. Leukoc. Biol. 60(5):658-666, 1996.
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