Technical Data
C2099-65G
CCR1 (Chemokine Receptor 1, CC-CKR-1)
Description:
Cellular Localization: Cell Membrane

Positive Control: Immunocytochemistry on human peripheral blood leukocytes.

Applications:
Suitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanGoat
Concentration:
~1mg/ml
Immunogen:
Synthetic peptide: TEDYDTTTEFDYGDATPC, corresponding to amino acids 7 - 24 of Human CCR1. Epitope: N-terminal extracellular domain of human CCR1.
Purity:
Purified by immunoaffinity chromatography.
Form
0.1% Sodium Azide PBS, 1mg/ml BSA. pH 7.2
Specificity:
Peptide sequence is < 50% identical to other chemokine receptors in this region. Species Crossreactivity: Crossreacts with Human. Does not crossreact with Mouse. Expected to crossreact with Macaque Monkey (88% identity with immunogen) due to sequence homology.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Neote K et al. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 72:415-25 (1993).
2. Su, S.B., et al. Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression of various types of leukocytes. J. Leukoc. Biol. 60(5):658-666, 1996.