Cellular Localization: Cell Membrane
Positive Control: Immunocytochemistry on human peripheral blood leukocytes.
Suitable for use in ELISA, Western Blot and Immunocytochemistry. Other applications not tested.
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
|Synthetic peptide: TEDYDTTTEFDYGDATPC, corresponding to amino acids 7 - 24 of Human CCR1. Epitope: N-terminal extracellular domain of human CCR1.|
|Purified by immunoaffinity chromatography.|
|0.1% Sodium Azide PBS, 1mg/ml BSA. pH 7.2|
|Peptide sequence is < 50% identical to other chemokine receptors in this region. Species Crossreactivity: Crossreacts with Human. Does not crossreact with Mouse. Expected to crossreact with Macaque Monkey (88% identity with immunogen) due to sequence homology. |
|Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.|
Neote K et al. Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor. Cell 72:415-25 (1993). <7679328>|
2. Su, S.B., et al. Preparation of specific polyclonal antibodies to a C-C chemokine receptor, CCR1, and determination of CCR1 expression of various types of leukocytes. J. Leukoc. Biol. 60(5):658-666, 1996.