Technical Data
C2267-32
CD16 (Fc gamma RIII alpha, NK cells)
Description:
CD16 is the low affinity Fc gamma III present on Large Granular Lymphocytes (LGL), NK cells, granulocytes and a macrophage subpopulation. It is a late myeloid differentiation antigen and expressed on Chronic Myeloid Leukemia cells. The antibodies LGL/1 and LGL/3 show a polymorphism for granulocytes. LGL/1 reacts with granulocytes of a proportion of the human population and LGL/3 reacts with the granulocytes of another proportion of the population. The nature of this polymorphism of granulocytes has not yet been revealed.

Applications:
Suitable for use in ELISA, Immunohistochemistry, Immunofluorescence, Flow Cytometry and Immunoprecipitation. Other applications not tested.

Recommended Dilutions:
Immunohistochemistry: Frozen sections
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a5B11Affinity Purified
SizeStorageShippingSourceHost
100ug-20°CBlue IceMouse
Concentration:
~1mg/ml
Immunogen:
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 0.01% sodium azide.
Specificity:
Recognizes CD16 antigen. Species Crossreactivity: human, rat and mouse
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.