Technical Data
C2443-86A
CD98
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Technical Data |
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C2443-86A |
CD98 |
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Description: CD98 (also known as fusion regulatory protein-1, FRP-1) is widely distributed on hemopoietic and non-hemopoietic cells. The levels of CD98 expression is very high on most cell lines but is low on platelets and granulocytes. CD 98 expression is increased on lymphocytes after their activation. Erythrocytes do not express CD98. CD98 is a disulfate-linked 125kD heterodimeric membrane glycoprotein that is composed of an 80-90kD glycosylated heavy chain and a 40kD nonglycosylated light chain. It may be involved in the regulation of cellular activation. Applications: Suitable for use in Flow Cytometry, Immunohistochemistry and Immunoprecipitation. Other applications not tested. Recommended Dilution: Flow Cytometry: 1:50-1:200; 10ul labels 10e6 cells in 100ul. Immunohistochemistry: Frozen Optimal dilutions to be determined by the researcher. Recommended Secondary Reagent: I1904-06C: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo I1904-06H: IgG, H&L (HRP) (X-Adsorbed) Pab Gt xMo I1904-14C: IgG, Fc (HRP) Pab Gt xMo I1904-19C: IgG, F(ab’)2 (HRP) Pab Gt xMo Recommended Negative Control: I1904-78R: IgG1 Murine Negative Control Hybridoma: Spleen cells from immunized BALB/c mice were fused with cells of the SP2/0-Ag14 mouse myeloma cell line. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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