Technical Data
C2617-02B3
CENTA2 (Arf-GAP with Dual PH Domain-containing Protein 2, Centaurin-alpha-2, Cnt-a2, ADAP2)
Description:
Centaurin alpha 2 is a potential GTPase-activating protein for the ADP ribosylation factor family. It binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). It possesses a stoichiometry of two binding sites for InsP4 with identical affinity.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Immunohistochemistry (Paraffin): 5-10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to C-RLTASTESGRSSR, from human ADAP2, at C-terminal (NP_060874.1).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Specificity:
Recognizes human ADAP2.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Jenne DE, Tinschert S, Stegmann E, Reimann H, N]urnberg P, Horn D, Naumann I, Buske A, Thiel G. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. Genomics. 2000 May 15;66(1):93-7.