		Technical Data
C2617-02B3	CENTA2 (Arf-GAP with Dual PH Domain-containing Protein 2, Centaurin-alpha-2, Cnt-a2, ADAP2)

Description:
Centaurin alpha 2 is a potential GTPase-activating protein for the ADP ribosylation factor family. It binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4). It possesses a stoichiometry of two binding sites for InsP4 with identical affinity.

Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Immunohistochemistry (Paraffin): 5-10ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab			Affinity Purified

Size		Storage	Shipping	Source	Host
100ug		-20°C	Blue Ice	Human	Goat

Concentration:

~0.5mg/ml

Immunogen:

Synthetic peptide corresponding to C-RLTASTESGRSSR, from human ADAP2, at C-terminal (NP_060874.1).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Specificity:

Recognizes human ADAP2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

1. Jenne DE, Tinschert S, Stegmann E, Reimann H, N]urnberg P, Horn D, Naumann I, Buske A, Thiel G. A common set of at least 11 functional genes is lost in the majority of NF1 patients with gross deletions. Genomics. 2000 May 15;66(1):93-7.