Technical Data
C4125-02
CHIP (Carboxy Terminus of Hsp70-interacting Protein, Antigen NY-CO-7, CLL-associated Antigen KW-8, E3 Ubiquitin-protein Ligase CHIP, HSPABP2, NY-CO-7, PP1131, SDCCAG7, STIP1 Homology and U Box-containing Protein 1, STUB1, UBOX1)
Description:
Applications:
Suitable for use in Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 0.3-1ug/ml
Optimal dilutions to be determined by the researcher.

Positive Control:
Human Muscle lysate

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceHumanGoat
Concentration:
~0.5mg/ml
Immunogen:
Synthetic peptide corresponding to DAFISENGWVEDY, from the C-terminus of the protein sequence according to NP_005852.
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH7.3, 0.5% BSA.
Specificity:
Recognizes human STUB1/CHIP. Species sequence homology: mouse.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Jiang J, Ballinger CA, Wu Y, Dai Q, Cyr DM, Hohfeld J, Patterson C. CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiiquitylation. J Biol Chem. 2001 Nov 16;276(46):42938-44. PMID: 11557750