Technical Data
C5839-73T
CLEC14A (C-type Lectin Domain Family 14 Member A, Epidermal Growth Factor Receptor 5, EGFR-5, C14orf27, EGFR5, UNQ236/PRO269) (APC)
Description:
CLEC14A (C-type lectin domain family 14 member A; also EGFR5) is a 51kD (predicted) member of the C-type lectin domain family of proteins. It is a type I transmembrane protein, apparently expressed in brain and about which little is known. Mature human CLEC14A is 469aa in length. It contains a 376aa extracellular region (aa22-397) and a 72aa cytoplasmic domain. The extracellular region shows one C-type lectin like domain (aa32-175) and an EGF-like region (aa245-287). Over aa2-397, human CLEC14A shares 66% and 81%aa identity with mouse and canine CLEC14A, respectively.

Applications:
Suitable for use in Flow Cytometry. Other applications not tested.

Recommended Dilution:
Optimal dilutions to be determined by the researcher.

Absorption: 620-650nm

Emission: 660-670nm

Storage and Stability:
May be stored at 4C before opening. DO NOT FREEZE! Stable at 4C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive..
TypeIsotypeCloneGrade
MabIgG2B12K67
SizeStorageShippingSourceHost
100Tests4C Do Not FreezeBlue IceHumanMouse
Concentration:
Not determined
Immunogen:
Recombinant corresponding to aa22-397 from the extracellular domain of human CLEC14A expressed in NSO cell line.
Purity:
Purified by Protein G affinity chromatography.
Form
Supplied as a liquid in saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
Specificity:
Recognizes human CLEC14A.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.