Technical Data
COL2A1, CT (Collagen alpha-1(II) Chain, Alpha-1 Type II Collagen, Chondrocalcin)
Alpha-1 chain of type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutant forms of this protein are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.

Suitable for use in ELISA and Western Blot. Other applications not tested.

Recommended Dilution:
Western Blot: 1:1000
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
200ul-20CBlue IceHumanRabbit
As reported
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1209-1237 in the C-terminal region of human COL2A1, UniProt Accession #P02458.
Purified by Protein A affinity chromatography.
Supplied as a liquid in PBS, 0.09% sodium azide.
Recognizes human COL2A1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1.Olavarrieta,L., Clin. Genet. 73(3), 262-267 (2008). 2.McAlinden,A., Hum. Mutat. 29(1), 83-90 (2008). 3.Forzano,F., Am. J. Med. Genet. A 143(23), 2815-2820 (2007).