		Technical Data
C7903-89H	CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 (Corticotropin-releasing factor receptor 1 precursor, CRF1, CRFR, CRF-R, CRFR1, CRHR, CRH-R 1, CRHR1f, CRH-R1h )

Description:
Corticotrophin-Releasing Hormone Receptor 1 (CRHR-1), also known as CRFR-1, is a 7TM protein that belongs to the G protein-coupled receptor family 2. CRHR-1 is expressed in the brain and adrenal gland where it mediates corticotropin- induced effects on anxiety, depression, and stress-associated pathologies. The immunogen for this antibody corresponds to one of the four alternately spliced forms and has a 29aa deletion in the first cytoplasmic domain. Human CRHR-1 shares 97aa sequence identity with mouse and rat CRHR-1.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Type	Isotype	Clone	Grade
Pab	IgG		Affinity Purified

Size		Storage	Shipping	Source	Host
50ug		-20°C	Blue Ice	Human	Rabbit

Concentration:

~0.1mg/ml

Immunogen:

Synthetic peptide corresponding extracellular domain of to human CRHR1 at N-terminal (KLH).

Purity:

Purified by immunoaffinity chromatography.

Form

Supplied as a liquid in PBS, 0.1% sodium azide.

Specificity:

Recognizes human Corticotropin-Releasing Factor Receptor 1.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.