Technical Data
C7903-89H
CORTICOTROPIN RELEASING FACTOR RECEPTOR 1 (Corticotropin-releasing factor receptor 1 precursor, CRF1, CRFR, CRF-R, CRFR1, CRHR, CRH-R 1, CRHR1f, CRH-R1h )
Description:
Corticotrophin-Releasing Hormone Receptor 1 (CRHR-1), also known as CRFR-1, is a 7TM protein that belongs to the G protein-coupled receptor family 2. CRHR-1 is expressed in the brain and adrenal gland where it mediates corticotropin- induced effects on anxiety, depression, and stress-associated pathologies. The immunogen for this antibody corresponds to one of the four alternately spliced forms and has a 29aa deletion in the first cytoplasmic domain. Human CRHR-1 shares 97aa sequence identity with mouse and rat CRHR-1.

Applications:
Suitable for use in Immunohistochemistry. Other applications not tested.

Recommended Dilution:
Immunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
PabIgGAffinity Purified
SizeStorageShippingSourceHost
50ug-20CBlue IceHumanRabbit
Concentration:
~0.1mg/ml
Immunogen:
Synthetic peptide corresponding extracellular domain of to human CRHR1 at N-terminal (KLH).
Purity:
Purified by immunoaffinity chromatography.
Form
Supplied as a liquid in PBS, 0.1% sodium azide.
Specificity:
Recognizes human Corticotropin-Releasing Factor Receptor 1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.