Technical Data
Cullin 1 (CUL-1)
Cullins (1, 2, 3, 4a, 5 and 7) are a family of proteins that assemble a large number of ubiquitin ligases to catalyse polyubiquitiation, as well as binding to various specific factors to recruit substrates. Cullin 1 (CUL 1) is an essential component of SCF E3 Ubiquitin ligase complex which mediates the ubiquitation of proteins involved in cell cycle progression, signal transduction and transcription.

Suitable for use in ELISA. Other applications not tested.

Recommended Dilution:
ELISA: 1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
PabIgGAffinity Purified
1mg-20CBlue IceHumanRabbit
As reported
Synthetic peptide (DGEKDTYSYLA) corresponding to aa742-752 of human Cullin 1
Purified by Protein G affinity chromatography.
Supplied as a liquid in PBS, pH 7.2.
Recognizes human CUL 1
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
Michel, J.J. & Xiong, Y. (1998) Cell Growth Differ. 9,435-449. Zheng, N. et al. (2002) Nature 416, 703-709. Jackson, P.K. & Eldridge, A.G. (2002) Mol. Cell. 9,923-925.