Technical Data
CXCL11, Recombinant, Human (Chemokine (C-X-C Motif) Ligand 11, b R1, H174, Interferon-inducible T Cell Alpha Chemoattractant, I-TAC, Interferon gamma Inducible Protein 9, IP-9, MGC102770, Small Inducible Cytokine B11, SCYB11, SCYB9B)
Molecular Biology Storage: -20CShipping: Blue Ice
I-TAC (Interferon-inducible T-cell alpha chemoattractant), otherwise known as CXCL11, is a member of the CXC chemokine family, which signals through binding to CD183 (CXCR3), and is regulated by interferon gamma and beta. I-TAC is highly expressed by peripheral blood leukocytes, the pancreas and liver, and acts as a potent chemoattractant for IL-2 activated T cells, as well as a natural antagonist for CD195 (CCR5).

E. coli

Suitable for use in Functional Assays. Other applications not tested.

Biological Activity:
Determined by its ability to chemoattract IL-2 activated T cells using a concentration range of 0.1-10ng/ml.

Endotoxin: 1EU/ug

Molecular Weight: 8.3kD (73 amino acid residues)

Storage and Stability:
Lyophilized powder may be stored at -20C. Reconstitute with sterile buffer or ddH2O. Aliquot and store at -20C. Reconstituted product is stable for 6 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight:
Source: E. coli
Purity: 98% (SDS PAGE and HPLC)
Concentration: ~0.1mg/ml
Form: Supplied as a lyophilized powder. Reconstitute in 200ul distilled water.

Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.