Technical Data
C9100-15E
Cytomegalovirus, 65kD Late Major (CMV pp65, 65kD Matrix Phosphoprotein, 65kD Phosphoprotein, HCMV, Human Herpes virus 5, HHV-5, HHV5, HHV5wtgp077, PP65, Tegument Protein pp65, Tegument Protein UL83, UL83)
Description:
The 65kD late major matrix protein of the cytomegalovirus (CMV) is a member of the Herpes virus family. CMV is a DNA virus that is widespread in the general population and characterized by its ability to give rise to persistent latent infections. The virus is the largest of the Herpes viruses and has the largest genome of any known virus. CMV is transmitted by the parenteral route and persists latently in circulating leukocytes and endothelial cells lining the walls of blood vessels. CMV lyses cells by disrupting the cytoskeleton and causing massive cell enlargement.

Applications:
Suitable for use in Immunofluorescence and Western Blot. Other applications not tested.

Recommended Dilutions:
Immunofluorescence: 1:10-1:50
Western Blot: 1:10-1:50
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
TypeIsotypeCloneGrade
MabIgG2a10B2656Affinity Purified
SizeStorageShippingSourceHost
100ug-20CBlue IceMouse
Concentration:
~0.1mg/ml
Immunogen:
Semi-pure Cytomegalovirus lysate
Purity:
Purified by Protein A affinity chromatography.
Form
Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.09% sodium azide.
Specificity:
Recognizes the 65kD late major matrix protein of the Cytomegalovirus (CMV).
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
1. Hunninghake, G. W. et al. (1999) Cytomegalovirus Infection. Regulation of inflammation. Am. J. Respir. Cell Mol. Biol. 21: 150152. 2. Griffiths, P. D. (2002) The 2001 Garrod lecture. The treatment of cytomegalovirus infection. J. Antimicrob. Chemother. 49: 243253.