Technical Data
DSG1, ID (Desmoglein-1, Cadherin Family Member 4, Desmosomal Glycoprotein 1, DG1, DGI, Pemphigus Foliaceus Antigen, CDHF4)
Desmosomes are a type of intercellular junction between epithelial, myocardial, and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein isoforms have been identified: DSG1, DSG2 and DSG3; all members of the cadherin cell adhesion molecule family. DSG1 has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus foliaceus.

Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.

Recommended Dilution:
ELISA: 1:32,000
Immunohistochemistry (Formalin fixed paraffin embedded): 3.75ug/ml
Optimal dilutions to be determined by the researcher.

Storage and Stability:
May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
PabIgGAffinity Purified
50ug-20CBlue IceHumanGoat
Synthetic peptide C-YTTSDTLKPSVHVHD from an internal region of human DSG1.
Purified by immunoaffinity chromatography.
Supplied as a liquid in Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Recognizes human DSG1.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.